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6.3 Quadrupole mass spectrometers (QMS) - Pfeiffer

At extremely low pressures, particularly in the UHV range, open ion sources are used which have a particularly small surface area and therefore low outgassing rates (grid ion source). Due to the low gas densities, secondary electron multipliers (SEM) that are arranged perpendicular to the axis of the quadrupole must be used as detectors.

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using quadrupole/time-of-flight mass spectrometry on

particularly useful to follow a fragmentation cascade. Recently, the combination of the quadrupole mass analyser with a time-of-flight mass analyser (QqTOF) has been described [8,9]. QqTOF is particularly powerful to obtain product ion spectra at medium resolution with the possibil-ity of accurate mass measurement of the fragments. This

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Quadrupole Mass Analyzer - an overview

Quadrupole mass analyzers are sometimes referred to as mass filters due to their ability to select ions of a single m/z value for analysis. Although they are inferior to magnetic sector instruments in terms of sensitivity, resolution, and upper mass range, their ease of use, relative affordability, compact size, and ability to be readily interfaced with GC or LC systems have rendered them the most widely used mass

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Quadrupole mass analyzer - mass spectrometry .. Info

2020-5-16  A quadrupole mass analyzer acts as a mass - selective filter and is closely related to the quadrupole ion trap, particularly the linear quadrupole ion A quadrupole or quadrapole is one of a sequence of configurations of things like electric charge or current, or gravitational mass

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Food Metabolomics No. C238 Quadrupole Mass

2021-6-30  Quadrupole Mass Spectrometer (Part 2) Metabolomics is a scientific field in which the differences in multiple sample groups are clarified by comprehensively ... considerable attention, particularly in the beer market. Together with improvement of the manufacturing process,

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The quadruple mass filter: Basic operating concepts

2016-1-21  quadrupole mass analyzers as a method of performing mass spectrometry-mass spectrometry (MS-MS) experiments (6-8). A third useful feature of the quadrupole mass analyzer is the mechanical simplicity of the instrument. Unlike many other types of mass analyzers, quadrupole devices do not rely on the use of magnetic fields for their mass-discriminat-

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Development of Quadrupole Mass Spectrometers Using

2014-6-13  Development of Quadrupole Mass Spectrometers Using Rapid Prototyping Technology Boris Brkic´,a Neil France,a Adam T. Clare, bChris J. Sutcliffe, Paul R. Chalker,b and Stephen Taylora a Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, United Kingdom b Department of Engineering, University of Liverpool, Liverpool, United Kingdom

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Quadrupole mass spectrometers in the past 30 years

2019-10-29  things have changed with quadrupole mass spectrometers (QMS) over the last 30 years. They have become more compact, durable, versatile and digital. Initially used primarily in research, QMS are nowadays utilized in the semiconductor industry, freeze-drying or

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Quadrupole mass spectrometer - Canadian Patents

A quadrupole mass spectrometer as claimed in claim 2 which further includes a mass of material attached to the first grid means on the axis for stopping particles travelling along the axis. 5. A quadrupole mass spectrometer as claimed in claim 4 which further includes a shield having a circular aperture located symmetrically about the axis between the other end of the rods and the first grid.

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(PDF) Triple Quadrupole Mass Spectrometry for Direct ...

The high sensitivity of the MS/MS technique with quadrupoles depends particularly on the highly efficient low energy collision-induced dissociation process in the strong focusing RF quadrupole field.

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Quadrupole mass analyzer - mass spectrometry .. Info

2020-5-16  A quadrupole mass analyzer acts as a mass - selective filter and is closely related to the quadrupole ion trap, particularly the linear quadrupole ion A quadrupole or quadrapole is one of a sequence of configurations of things like electric charge or current, or gravitational mass

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Quadrupole mass spectrometers in the past 30 years

2019-10-29  The first quadrupole mass spectrometers on the market included an integrated control unit in a 19 inch rack connect-ed via cable to the analyzer and other modules such as a high-frequency generator. Figure 1 shows the QMS 420 quad-rupole control unit commonly used at the end of the 1980s. This device was operated either completely via the control

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Food Metabolomics No. C238 Quadrupole Mass

2021-6-30  Quadrupole Mass Spectrometer (Part 2) Metabolomics is a scientific field in which the differences in multiple sample groups are clarified by comprehensively ... considerable attention, particularly in the beer market. Together with improvement of the manufacturing process,

More

Development of Quadrupole Mass Spectrometers Using

2014-6-13  Development of Quadrupole Mass Spectrometers Using Rapid Prototyping Technology Boris Brkic´,a Neil France,a Adam T. Clare, bChris J. Sutcliffe, Paul R. Chalker,b and Stephen Taylora a Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool, United Kingdom b Department of Engineering, University of Liverpool, Liverpool, United Kingdom

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A Novel Tandem Quadrupole Mass Analyzer - CORE

2017-1-28  stability regions are described. Operation in the third stability region is particularly advanta-geous because the tandem analyzer exhibits good abundance sensitivity on the low and high mass sides under conditions where a single quadrupole produces a long peak tail on at least one side.

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Quadrupole mass spectrometer - MKS Instruments, Inc.

2020-11-9  This invention relates generally to mass spectrometers, and more particularly to quadrupole mass spectrometers. BACKGROUND OF THE INVENTION. Quadrupole mass spectrometers are known. A portion of a prior art quadrupole mass spectrometer is shown in FIG. 1 of the drawings. A ground plate 10 supports an electron source filament 12 via two ...

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Increasing the Upper Mass/Charge Limit of a

2019-3-14  Quadrupole ion traps (QITs) [], both 3-D and linear, are widely used in mass spectrometry (MS) in part due to their small size and versatility in executing multi-stage mass spectrometry experiments (i.e., MS n), albeit with moderate-to-low resolution at usual scan rates [].Ion traps are particularly

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A novel tandem quadrupole mass analyzer Journal of

2020-1-1  A new “tandem mass analyzer” is described. Two quadrupole mass filters are operated in series. Each is operated at low resolution and a small mass offset is introduced between the two quadrupoles so that the pair operate together to give higher resolution. The resolution of the tandem analyzer can be changed by changing the mass offset. The transmission is highest when the

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As the triple quadrupole turns 40, mass spec gurus

As the triple quadrupole turns 40, mass spec gurus look back on what it’s meant to chemistry. Enke (left) and Yost shown with the triple quadrupole they built at Michigan State in 1978. Christie ...

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(PDF) Mass Spectrometry: Analysers an Important Tool

2018-8-31  The quadrupole ion trap, often used in conjunction with a quadrupole mass filter, remained a laboratory curiosity until 1979 when, at the American Society for Mass Spectrometry Conference in ...

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Quadrupole mass analyzer - mass spectrometry .. Info

2020-5-16  A quadrupole mass analyzer acts as a mass - selective filter and is closely related to the quadrupole ion trap, particularly the linear quadrupole ion A quadrupole or quadrapole is one of a sequence of configurations of things like electric charge or current, or gravitational mass

More

Quadrupole mass spectrometer - MKS Instruments, Inc.

2020-11-9  This invention relates generally to mass spectrometers, and more particularly to quadrupole mass spectrometers. BACKGROUND OF THE INVENTION. Quadrupole mass spectrometers are known. A portion of a prior art quadrupole mass spectrometer is shown in FIG. 1 of the drawings. A ground plate 10 supports an electron source filament 12 via two ...

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A Novel Tandem Quadrupole Mass Analyzer - CORE

2017-1-28  stability regions are described. Operation in the third stability region is particularly advanta-geous because the tandem analyzer exhibits good abundance sensitivity on the low and high mass sides under conditions where a single quadrupole produces a long peak tail on at least one side.

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Extended Mass Range Triple Quadrupole for Routine

2018-10-16  The Agilent 6495B Triple Quadrupole LC/MS system has a mass range of 3,000 u, which is useful for detecting high m/z peptide ions. One benefit of using high m/z precursor or product ions, particularly in a complex digest, is these ions have less background noise compared to those with low m/z. Some high m/z product ions may provide

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HMT Quadrupole Mass Spectrometer for Vacuum

A dual mode RGA system for vacuum diagnostics and process monitoring. The Hiden HMT quadrupole mass spectrometer is a unique dual mode RGA system capable of operating at pressures up to 5×10-3 mbar without the need for differential pumping. Operation at this pressure is achieved using a specially designed ion source/quadrupole filter combination and software which corrects for abundance non ...

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Rapid screening and characterization of drug metabolites ...

mass spectrometry (LC/MS/MS) is particularly suitable for ... path using the final quadrupole as a linear ion trap mass spectrometer (QqLIT). The mass range is m/z 5–1700 in quadrupole mode and m/z 50–1700 in linear ion trap mode. The various scan modes of the instrument are summarized

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DESIGN AND PERFORMANCE OF A HIGHLY COMPACT

2014-6-11  A compact single quadrupole mass spectrometer with performance characteristics that rivals that of conventional instruments. Footprint allows the direct integration of the mass spectrometer into a UPLC chromatography stack. Designed with ease-of-use as a primary goal to allow even novice users to acquire good quality data. Figure 1.

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Smart Note: Triple Quadrupole ICP-MS or Single

2020-8-5  Triple Quadrupole ICP-MS or Single Quadrupole ICP-MS? Which Instrument is Right for Me? SmartNotes iCAP TQ ICP-MS The IUPAC definition of a triple quadrupole mass spectrometer is a ‘tandem mass spectrometer comprising two transmission quadrupole mass spectrometers in series, with a (non-selecting) RF-only quadrupole (or other multipole) between them to act as a collision cell’1.

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Quadrupole detection FT‐ICR mass spectrometry

2020-11-24  Mass resolving power is one of the key features of Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), which enables the molecular characterization of complex mixtures. Quadrupole (2ω) detection provides a significant step forward in FT-ICR MS performance, as it doubles the resolving power for a given signal acquisition time.

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pQA Portable Quadrupole Analyser Gas Monitoring

Designed for analysis of dissolved gases in water, and sediments for use in the field at the riverbank, on boats and in mobile laboratories. The Hiden pQA portable gas analyser is a versatile mass spectrometer and offered with a range of interchangeable sampling inlets to suit a broad application range.

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